Study proves positive effects of probiotics

The colonoscopy is one of the most important preventive examinations to maintain health, especially after the age of 50, and to identify possible tissue changes in good time.
Although the technical and scientific development of colonoscopy has made great progress, many people still shy away from this important examination: Digestive problems that have been experienced personally or reported by family and friends after the colonoscopy are often a reason not to have the colonoscopy performed.
The reason for constipation, flatulence and the like lies in a microbiome that has been massively changed by the intestinal lavage.

"We would like to do our part to ensure that everyone over the age of 50 regularly has a colonoscopy," explains Mag. Anita Frauwallner, Managing Director of Institut Allergosan. Because taking a multispecies probiotic can make a significant contribution to alleviating these unpleasant side effects of a colonoscopy. In order to obtain a scientifically sound basis for this role of the multispecies probiotic as an "intestinal fire brigade", the Allergosan Institute commissioned a study, the results of which are now making people sit up and take notice.

In 8 participating clinics in Germany, it was examined to what extent the digestion of the patients had changed after the colonoscopy and what influence a four-week intake of probiotics or placebo had on it. In addition, it was analyzed to what extent the probiotic affects the diversity of the microbiome: the more diverse it is, the healthier and more resilient the person is. The result: After only 4 weeks, the so-called alpha diversity, the diversity of the microbiome in the intestine of the respective patient, was actually significantly higher in the probiotic group than in that of the placebo group.


Principal investigator and study author Prof. Joachim Labenz draws a positive balance of taking a multispecies probiotic after the colonoscopy: “If someone wants to do something good for themselves after a colonoscopy, you can say: Take a special probiotic for four weeks to support them your gut and your microbiome. That's certainly a conclusion I would draw from the study's data.”



Labenz, J. et al. A multispecies probiotic shows a positive effect on the intestinal microbiome and reduces intestinal symptoms after oral intestinal lavage for screening colonoscopy: randomized, double-blind, placebo-controlled, multicenter study (COLONIZE). Z Gastroenterol. 60(08): 643–643 (2022)