Fermentation, CIP & SIP processes in pharmaceutical plants

When extracting active ingredients using cell, yeast and bacterial cultures in bioreactors and fermentation systems, there are special requirements for stirring, gassing, heat and gas transfer that must be taken into account. Proper cleaning and sterilization using CIP/SIP systems is also of utmost importance for liquid-aseptic processing.
For precisely these challenges, ZETA – in cooperation with the Human Technology Cluster (HTS) – has developed a tailor-made training offer.

training contents

• What is fermentation and why is it necessary in the upstream process?
• What conditions do microorganisms usually require?
• Which media must be fed to a fermenter?
• Which parameters are controlled in a fermenter?
• Fermenter Design: What is Needed in a Fermenter

Lecturer

DI Dr. Hubert Sommerhofer

TIP: Do you want to deepen your knowledge even further? In the independent 2-day training module “Challenges in pharmaceutical plant engineering” you will learn everything about the technical and regulatory basics in pharmaceutical plant engineering. More information about the training extension, which takes place on November 11th and 12th directly before “Fermentation, CIP & SIP processes in pharmaceutical plants”, can be found here.

We ask for your understanding that the training can only take place once a minimum number of participants has been reached. Cancellation is possible up to one week before the start.

• Need for CIP, explanation & purpose of CIP process steps
• Which medium is used for which CIP step?
• Important measurements during the CIP process of a unit
• Need for SIP?
• sterilization methods
• Parameters and important measurements for a successful SIP (with pure steam)
• Important design details for the SIP of a unit/skid
• Description of SIP process steps and SIP on different fermenters